Getting busy on the proof

“Faced with the choice between changing one’s mind and proving there is no need to do so, almost everyone gets busy on the proof.” | John Kenneth Galbraith (quoted in Poor Charlie’s Almanack)

Funny and wise.

John Kenneth Galbraith’s quotes have all gotten me asking the same question – how often do I do this?

The answer is more often than I’d like to admit.

Solar supercycle

The Exponential View team pulled together a thought provoking interactive resource on the Solar supercycle.

You can see the impact of learning curve projections as you tweak assumptions. The trend so far alone is fascinating however – as solar capacity increases, it is becoming exponentially cheaper.

It is a self-reinforcing cycle. The same forces that shaped the computing flywheel and made it ubiquitous are at work here.

Cost reduction creates demand. Demand drives deployment. Deployment drives more learning curves and cost reduction.

It is fascinating to think about the impact of lower costs. Suddenly, technologies that were out of reach given how energy expensive they were – from desalination to sustainable aviation fuel – become possible.

Positive exponential changes are fascinating to behold. And as far as the solar supercycle goes, we’re just getting started.

A few powerful charts

Derek Thompson shared a few fascinating charts.

Teenagers in the US aren’t reading.

They (along with adults) aren’t partying either.

But everyone is watching more YouTube (and TikTok).

The link between spending time on TikTok and most brain functions – from attention to memory to reasoning to inhibitory control are all negative. TikTok is melting our brain.

We’re seeing more young adults dislocated from both the economy and society.

Jonathan Haidt unearthed a fascinating insight among 12th graders – finding that conservatism and religion helped reduce the impact of this dislocation.

His hypothesis is that conservatism and religion might offer a binding moral matrix that protects young people from a rapidly changing world. While progressive moralities aim to grant people more freedom to “create their own identities”, this freedom is likely causing anxiety.

Societal dislocation and the legalization of gambling presents a toxic combination.

And this one continues to blow my mind – leading to the largest measles outbreak in the US in 20 years.

Sam Walton’s Saturday morning meeting

Every Saturday morning, Wal-Mart founder Sam Walton gathered his team for the same ritual.

First, they’d review the week’s sales in detail. Then, they’d discuss one question: what is a competitor doing that we should be paying attention to?

Employees would share observations from visits to Kmart, Walgreens, Sears. There was one strict rule: you could only talk about what competitors were doing right. Things that were smart and well executed.

Walton didn’t care what they were doing wrong. That couldn’t hurt him. What he cared about was not letting any competitor get more than a week’s advantage on something innovative.

It’s a beautiful way to institutionalize curiosity. And to steer a room full of people away from the instinct to talk about why they’re better – toward the harder, more useful question of what they can learn.

The Machine Tool You Haven’t Bought

From an old Warner & Swasey advertisement, quoted in Poor Charlie’s Almanac: “The person who needs a new machine tool and hasn’t bought it is already paying for it.”

It got me thinking about the suite of incredible tools available to knowledge workers now – if you aren’t using them, you’re likely already paying for it.

No diet wins

After 40 years of running experiments on the impact of diets on nutrition and health, Stanford University’s Christopher Gardner came to a simple conclusion – diet wars are a distraction.

I loved this distillation of the five lessons he shared –

(1) No single diet wins across the board. Low-carb, low-fat, vegan, and Mediterranean diets all produce similar average outcomes when matched for quality.

(2) Individual variation in response to diet is enormous – and mostly unexplained by genetics, insulin status, or any other single factor researchers have identified.

(3) Added sugar and refined grains are the dietary factors with the clearest, most consistent evidence for harm – and the ones most worth reducing regardless of which diet pattern you follow.

(4) The best diet for you is the one you can sustain. But that doesn’t mean the standard American diet – it means finding the highest-quality version of an eating pattern you can actually stick to long-term.

(5) There is more scientific consensus around the fundamentals of healthy eating than headlines suggest. Eat whole foods, plenty of vegetables, and legumes. Avoid added sugar and refined grains. Nearly every serious dietary framework agrees on this.

Apo(B), Lp(a), and CHIP

Dr Eric Topol wrote about a big milestone recently – Cardiology professional organizations have finally recognized that Apo(B) and Lp(a) should be part of the lipid panel.

After reading Dr Attia’s Outlive, I’d asked for these as part of my panel. But I’d been denied – so here’s hoping that changes. In his words – “Think of how many people would have been identified at high-risk for atherosclerosis and cardiovascular events who were missed all this time because the guidelines didn’t keep up with the body of knowledge.

Dr Topol’s post goes on to advocate for the CHIP test as part of the lipid panel.

CHIP, which stands for clonal hematopoiesis of indeterminate potential, refers to presence of myeloid blood cells with a driver gene mutation (with a frequency of ≥ 2%) without any clinical criteria of a blood cancer. It turns out CHIP is a major biomarker, not just for blood cancer (an 11-fold risk of a blood malignancy, or absolute 0.5% risk per year), but also for heart disease, blood clot events such as stroke and pulmonary embolism, and many other chronic illnesses 

He makes the case with a simple chart that shows that the risk of heart rate with CHIP present goes up 1.8x.

You can also see the trend clearly here.

I’m hoping we’ll continue to see more testing here and will hopefully see it in the guidelines sooner than 8 years later.